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Studying inhibitory brain networks of the mouse sense of smell “Unlike sight, hearing or other senses, the sense of smell in the mouse detects discrete scents from a large array of molecules,” said Arenkiel, who is also a McNair Scholar at Baylor. Mice can detect a vast number of scents thanks in part to a complex network of inhibitory neurons. Inhibitory neurons are the most abundant type of cells in the mouse brain area dedicated to process scent. To support this network, newly born inhibitory neurons are continually added and integrated into the circuits. Arenkiel and colleagues followed the paths of these newly added neurons in time to determine how inhibitory circuits develop. First, they genetically labeled the cells so they would glow when the neurons were active. Then, they offered individual scents to the mice and visually recorded through a microscope the areas or networks of the brain that glowed for each scent the live, anesthetized animal smelled. The scientists repeated the experiment several times to determine how the networks changed as the animal learned to identify each scent. Surprising result The scientists expected that inhibitory networks would mature in a way similar to that of excitatory networks.
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View photos The aggregate gross proceeds of the Offering amounts to $1,533,745.50 and will be used by the Corporation to incur exploration expenses on its mining properties located in the province of Quebec. http://www.youtube.com/watch?feature=kp&v=Pf7JuJcVzQUMichel Baril , directors of the Corporation, which constitute “related parties transactions” within the meaning of Regulation 61-101 respecting Protection of Minority Security Holders in Special Transactions (“Regulation 61-101″) and TSX Venture Exchange Policy 5.9 Protection of Minority Security Holders in Special Transactions. Bourassa or Mr. Baril nor the fair market value of the consideration paid exceed 25% of the Corporation’s market capitalization. None of the Corporation’s directors has expressed any contrary views or disagreements with respect to the foregoing. A material change report in respect to this related party transaction will be filed by the Corporation but could not be filed earlier than 21 days prior to the closing of the Offering due to the fact that the terms of the participation of each of the non-related parties and the related party in the Offering were not confirmed. All securities issued pursuant to this Offering are subject to a restricted period of four months and a day. The Corporation paid each of Canaccord Genuity Corp. and Red Cloud Klondike Strike Inc., acting as finders pursuant to the Offering (the “Finders”), in consideration for their services rendered in connection with the Offering, a cash commission of $12,040 and granted to each 34,400 Finders’ Options to purchase up to 34,400 common shares in the capital stock of the Corporation, at a price of $0.35 per common share, within a delay of 18 months after the closing of the Offering. The securities issued under the Offering have not been registered under the United States Securities Act of 1933 (the “Act”) or any state securities laws and, accordingly, may not be offered or sold to, except in compliance with exemptions from the registration requirements of the Act and applicable state securities laws.
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